Cholinergic receptors are found in both nerve cells,
and non-nerve cells (such as those in the lungs). Critically, if nicotine fuses
with cholinergic receptors on the surfaces of lung cancer cells, they are
nourished to go on to divide and spread. (There is a profound impact of this
scenario on non-small cell lung cancer cells).
Nicotine replacement therapy products (NRT) contain
nicotine and raise nicotine levels in the blood - this can make it harder to
quit. When these products
are used over a long period, they may actually encourage the formation of new
nicotine-cholinergic receptors.
Ref: Brautbar, N. (1995) ‘Direct Effects of Nicotine on the Brain: Evidence for Chemical Addiction’ Archives of Environmental Health (July 1): 263, as cited in Novelguide, Nicotine [online] http://www.novelguide.com/a/di scover/chfa_03/chfa_03_00349.html (Accessed November 8th 2011).
Ref: Brautbar, N. (1995) ‘Direct Effects of Nicotine on the Brain: Evidence for Chemical Addiction’ Archives of Environmental Health (July 1): 263, as cited in Novelguide, Nicotine [online] http://www.novelguide.com/a/di scover/chfa_03/chfa_03_00349.html (Accessed November 8th 2011).
‘Nicotine promotes the growth of new blood vessels and
can also stimulate tumor growth and the build-up of plaque inside arteries’
Ref: Stanford University School of Medicine (July 30th 2001), ScienceDailyR[online] http://www.sciencedaily.com/releases/2001/07/010730075130.htm (Accessed November 25th 2011)
NICOTINE REPLACEMENT THERAPY PRODUCTS AND THE POSSIBLE
LINK WITH THE PROMOTION OF CANCER CELLS THROUGH ANGIOGENESIS (NEW BLOOD VESSEL
DEVELOPMENT) CANCER DEVELOPMENT
Nicotine has been linked to cancer in various ways,
and at the present time, there is a debate as to whether nicotine acts as a
tumour promoter. Long term use of Nicotine Replacement Therapy (NRT) patches
and other NRT products may, (according to a number of research studies on
animals), promote cancer through new blood vessel development (angiogenesis).
‘Angiogenesis performs a critical role in the development of cancer. Solid
tumours smaller than 1 to 2 cubic mm are not vascularized [not supplied with
blood vessels]. To spread, they need to be supplied by blood vessels that bring
oxygen and nutrients and remove metabolic wastes’
Ref: Angio World [online]
http://www.angioworld.com/cancer.htm (Accessed November 25th 2011)
For more detailed information visit:
http://www.ncbi.nlm.nih.gov/pubmed/19841737
NICOTINE REPLACEMENT PRODUCTS AND MATERNAL SMOKING
‘We have found distinct links between cigarette
smoking or even using nicotine patches or gum and the long-term harm for the
child’
Dr DaLiao Xiao, Loma Linda University School of
Medicine,California
Ref: Wiley-Blackwell (July 20th 2011) ‘How maternal
smoking or nicotine use increases the risk of cardiovascular disease in later
life’ ScienceDailyR
[online] http://www.sciencedaily.com/releases/2011/07/110720210654.htm (Accessed November 1st 2011)
The contraindications, warnings and precautions linked
to NRT also make frightening reading:
http://www.rxmed.com/b.main/b2.pharmaceutical/b2.1.monographs/CPS-%20Monographs/CPS-%20(General
%20Monographs-%20N)/NICORETTE.html
You may now be asking yourself why after all these years, most of the general public are not aware of these dangers; and why there is so little research on long-term use of all the various forms of NRT. - The answer could lie in the same reason why the dangerous effects of smoking are still taking so long to reach everyone. Large brand names are incidentally, manufactured by ‘Big Pharma’ who are geared to make billions of dollars with these products, and as you can probably guess - the nicotine used is from the same tobacco plants as cigarettes. NRT does not form part of the protocol in "The Winning Way to Quit Smoking"
You may now be asking yourself why after all these years, most of the general public are not aware of these dangers; and why there is so little research on long-term use of all the various forms of NRT. - The answer could lie in the same reason why the dangerous effects of smoking are still taking so long to reach everyone. Large brand names are incidentally, manufactured by ‘Big Pharma’ who are geared to make billions of dollars with these products, and as you can probably guess - the nicotine used is from the same tobacco plants as cigarettes. NRT does not form part of the protocol in "The Winning Way to Quit Smoking"
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